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Two-Dimensional Preparative Liquid Chromatography Platform

Author: Published Date: 2026-03-13

In the fiercely competitive CXO industry, R&D efficiency, cost control, and experimental accuracy have long become the core competitiveness of enterprises. Are lengthy experiment cycles, resource waste from repeated trial and error, insufficient equipment utilization, and R&D personnel trapped in repetitive labor restricting the progress of your projects.Chromai's Two-Dimensional Preparative Liquid Chromatography Platform provides customized solutions tailored for CXO R&D, delivering "precise adaptation + efficient empowerment" to double R&D efficiency and significantly reduce costs, helping enterprises seize opportunities in the fierce market competition!



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PART 01 Customized Solutions Break Through Five Pain Points in Separation and Purification




01
Chromatographic Peak Focusing

Adopting an innovative combination of an auxiliary pump and a universal trap column, it accurately solves the problem of one-dimensional fraction diffusion, achieving a qualitative leap in two-dimensional peak shape. The universal trap column breaks application limitations, greatly expands the adaptation scenarios of the preparative platform, and meets more diverse experimental needs.

02
Improved Resolution

No compromise when facing complex and difficult-to-separate impurities! Flexibly adjust the flow path through valve switching technology, reduce the number of series-connected trap columns and chromatographic columns, compatible with the pressure resistance range of the instrument hardware. At the same time, it can be matched with chromatographic columns with smaller particle size and higher column efficiency, making difficult-to-separate impurities nowhere to hide and further improving separation accuracy.

03
Solvent Compatibility

The universal trap column brings a revolutionary breakthrough in solvent compatibility, easily realizing the free switching of multi-dimensional preparative modes such as reversed-phase/reversed-phase and reversed-phase/hydrophilic interaction, completely solving the problem of adaptation to different solvent systems, and making experimental design more flexible.

04
Balance Between Target Compounds and Impurities

Through customized instrument configuration, simultaneous multi-dimensional and multi-component preparation of target compounds and impurities is realized, taking into account the core needs of R&D and the requirements of impurity analysis. For trace impurities with low content, technologies such as multi-injection enrichment are adopted to greatly improve detection sensitivity, making trace impurities impossible to escape detection.

05
Intelligent Software Control

A variety of integrated automatic valves are optional, combined with highly compatible intelligent software, to realize automatic multi-valve switching and full-process automated operation. No frequent manual intervention is required, making the experimental process more standardized, the results more stable, and greatly reducing human operation errors.


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PART 02 Four Major Values Reshape the Pattern of CXO R&D Quality and Efficiency Improvement


Cycle Halved: Pretreatment Optimization Achieves Efficiency Leap

In traditional liquid chromatography experiments, lengthy pretreatment operations such as freeze-drying and rotary evaporation often become "stumbling blocks" that slow down R&D progress. Our solution greatly reduces such time-consuming operations by optimizing the pretreatment process, directly shortening the method development cycle by 50%. The delivery cycle of urgent projects can be accurately shortened, making enterprises more responsive in customer cooperation.

Cost Reduction: One-Time Compliance Eliminates Repeated Waste

The "invisible black hole" of R&D costs is often hidden in repeated experiments — sample retries, material consumption, and time loss caused by insufficient purity can accumulate to significantly increase project costs. With our precise separation technology and stable system performance, we avoid repeated experiments caused by purity issues from the source, not only saving precious experimental materials, but also eliminating the time cost caused by repeated operations, realizing fundamental control of R&D costs.

Resource Efficiency: Equipment Utilization Rate Doubles Directly

Equipment is the core asset of R&D, and its utilization rate directly determines the return on resource investment. Our two-dimensional preparative system brings a fundamental breakthrough: while completing the main separation task, it can simultaneously re-purify the collected fractions, allowing a single device to realize "double value" and directly doubling the equipment utilization rate. Without additional equipment purchase, the experimental output per unit time can be increased, enabling limited resources to create greater R&D value.

Manpower Liberation: 24-Hour Automation Unlocks Productivity

The energy of R&D personnel should focus on core work such as experimental design and result analysis, but they are often occupied by repetitive operations such as sample injection, separation, and collection. We can realize a 24-hour continuous automatic closed-loop process of sample injection, separation, and collection, which can operate stably without manual on-duty. This not only frees R&D personnel from tedious manual labor and focuses their energy on higher-value R&D links, but also makes the experimental process not limited by working hours, realizing an efficient R&D model of "people rest, machines don't stop".


From technological breakthrough to value realization, Chromai's Two-Dimensional Preparative Platform takes "saving manpower, reducing costs, improving efficiency, and ensuring accuracy" as the core, providing full-scenario adaptation and full-process empowerment solutions for CXO R&D. Whether it is accelerating project delivery, controlling R&D costs, improving experimental accuracy, or releasing manpower value, Chromai can be your reliable partner in R&D, helping enterprises run faster, more stably, and further on the CXO track!


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